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カタログNo : FCCH100106

FlowCellect(R)MitoDamage Kit

  • 包装: 1kit
  • 在庫状況: 受発
希望販売価格
(包装基準)
64,900円

※表示価格には消費税が含まれていません。

Luminex
  • 商品に関するお問合せ

The Guava(R) MitoDamage Kit ー100 Tests (Part Number: FCCH100106) includes:

MitoSense Red, a fluorescent cationic dye that accumulates in the mitochondria and indicates changes in mitochondrial potential. MitoSense Red is excitable by a red laser, with peak fluorescence at 650 nm. Uninduced cells with an intact mitochondrial membrane potential demonstrate high red off red fluorescence, while cells that have an impaired mitochondrial membrane potential give off lower red off red fluorescence.

Annexin V conjugated to the green fluourescent dye CF(R) 488A, which binds to phosphatidylserine (PS) on the surface of apoptotic cells. Annexin V is a calcium-dependent phospholipid binding protein with a high affinity for PS?a membrane component normally localized to the internal side of the cell membrane. It is conjugated to CF(R) 488A, which is excited by a 488 nm laser and emits at 525 nm. Control cells do not exhibit green fluorescence, while apoptotic cells demonstrate positive green fluorescence.

7-Aminoactinomycin-D (7-AAD), a fluorescent DNA intercalator that is membrane impermeant (and therefore binds to dead cells). The 7-AAD dye included in the kit monitors cell membrane permeability changes typically observed later in apoptosis, as well as necrotic cell death. 7-AAD is excluded from live, healthy cells as well as early apoptotic cells?these cells have low red fluorescence.

Together, these reagents allow researchers to obtain information on mitochondrial stress, as well as early, mid, and late apoptosis, in one simple assay.

The kit can distinguish multiple populations:

1. Live cells with intact mitochondrial membrane
2. Cells with dissipated membrane potential but no Annexin V or 7-AAD staining
3. Early apoptotic cells with dissipated membrane potential and Annexin V binding
4. Late apoptotic cells and dead cells with dissipated membrane potentials

The Guava MitoDamage kit provides a complete picture of mitochondrial and cell health, allowing correlation of mitochondrial damage to cell health. The entire assay can be performed in less than 30 minutes once samples are ready.

For Research Use Only. Not for use in diagnostic procedures.

CF is a registered trademark of Biotium.

カタログNo 商品名 包装 希望販売価格 大箱単位 在庫 備考
FCCH100106 FlowCellect(R)MitoDamage Kit 1kit

希望販売価格:64,900円

受発
カタログNo 商品名 包装 希望販売価格 大箱単位 在庫 備考
0500-4005 Guava(R)easyCyte(TM)5HT 1式

希望販売価格:7,900,000円

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0500-4007 Guava(R)easyCyte(TM)6HT-2L 1式

希望販売価格:9,480,000円

受発
0500-4008 Guava(R)easyCyte(TM)8HT 1式

希望販売価格:12,640,000円

受発
0500-4009 Guava(R)easyCyte(TM)5HT HPL 1式

希望販売価格:9,100,000円

受発
0500-4012 Guava(R)easyCyte(TM)12HT 1式

希望販売価格:17,220,000円

受発
0500-4015 Guava(R)easyCyte(TM)HT BG 1式

希望販売価格:13,540,000円

受発
0500-4020 Guava(R)easyCyte(TM)11HT 1式

希望販売価格:14,760,000円

受発
希望販売価格の変更(2019.12.5)
0500-4025 Guava(R)easyCyte(TM)HT BGR 1式

希望販売価格:16,150,000円

受発
0500-4030 Guava(R)easyCyte(TM)HT BGV 1式

希望販売価格:17,480,000円

受発
0500-5005 Guava(R)easyCyte(TM)5 1式

希望販売価格:5,530,000円

受発
0500-5007 Guava(R)easyCyte(TM)6-2L 1式

希望販売価格:7,110,000円

受発
0500-5008 Guava(R)easyCyte(TM)8 1式

希望販売価格:9,480,000円

受発
0500-5009 Guava(R)easyCyte(TM)5 HPL 1式

希望販売価格:6,770,000円

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